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plac is much more than a command-line arguments parser. You can use it to implement interactive interpreters (both on a local machine on a remote server) as well as batch interpreters. It features a doctest-like mode, the ability to launch commands in parallel, and more. And it is easy to use too!
imapautofiler applies user-defined rules to automatically organize messages on an IMAP server.
Everett is a configuration library for Python apps.