streamexpect - кроссплатформенная библиотека для потоков и сокетов

import serial
import streamexpect

# timeout=0 is essential, as streams are required to be non-blocking
ser = serial.Serial('COM1', baudrate=115200, timeout=0)

with streamexpect.wrap(ser) as stream:
  stream.write('\r\nuname -a\r\n')
  match = stream.expect_bytes('Linux', timeout=1.0)
  print(u'Found Linux at index {}'.format(match.start))